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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (2) Autor Venkateshvaran,K (2) Bragadeeswaran,S (1) Kanagarajan,U (1) Nalini,P (1) Pani Prasad,K (1) Purushottama,GB (1) Mais... Palavra-chave Hemolysis (2) Angiogenesis (1) Halichondria panicea (1) Human blood groups (1) Neuromodulation (1) Paw edema (1) Phagocytosis (1) Starfish (1) Toxicity (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (1) 2008 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Bioactivities of extracts from the marine sponge Halichondria panicea J. Venom. Anim. Toxins incl. Trop. Dis. Purushottama,GB; Venkateshvaran,K; Pani Prasad,K; Nalini,P. In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (2:1) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an... Tipo: Info:eu-repo/semantics/article Palavras-chave: Halichondria panicea; Phagocytosis; Neuromodulation; Hemolysis; Angiogenesis. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300007 On some toxinological aspects of the starfish Stellaster equestris (Retzius, 1805) J. Venom. Anim. Toxins incl. Trop. Dis. Kanagarajan,U; Bragadeeswaran,S; Venkateshvaran,K. Whole-body extracts in methanol were obtained from the starfish Stellaster equestris. The crude toxin was fractionated stepwise using diethylaminoethyl (DEAE) cellulose column chromatography. The crude toxin was lethal to male albino mice at a dose of 1.00 mL (containing 531.0 µg/mL protein) when injected intraperitoneally (IP) but the toxicity was abolished in all cases except one upon fractionation. The crude toxin and all the adsorbed fractions exhibited potent hemolytic activity on chicken, goat and human blood. However, group B human erythrocytes were resistant to lysis by all fractions and group O by most of the fractions. Paw edema in mice was caused by the crude toxin and all fractions. Pheniramine maleate and piroxicam blocked the toxicity when... Tipo: Info:eu-repo/semantics/article Palavras-chave: Starfish; Toxicity; Hemolysis; Human blood groups; Paw edema. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000300005 Registros recuperados: 2 Primeira ... 1 ... Última

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